Additional Information

Indications for Referral

• Hereditary Breast and Ovarian Cancer
• Hereditary Non-Polyposis Colon Cancer
• Familial Adenomatous Polyposis
• Cowden
• Li-Fraumeni
• Hereditary Melanoma
• Multiple Endocrine Neoplasia Type 1
• Multiple Endocrine Neoplasia Type 2

Identify a High Risk Patient
Refer to CINJ
Refer to Other Genetics Programs
Ordering Brochures

INDICATIONS FOR REFERRAL FOR CANCER GENETIC COUNSELING AND RISK ASSESSMENT
Created by Shelly Cummings, M.S., University of Chicago

Click here to download a one-page summary of Indications for Referral in a PDF format.

Note: Adobe Acrobat is required to open the PDF file. If you do not have the program installed, you can download it here.

Hereditary Breast and Ovarian Cancer (BRCA1, BRCA2)

• Breast cancer diagnosed in 2 or more close relatives < age 50
• Bilateral breast cancer diagnosed at any age
• Male breast cancer diagnosed at any age
• Breast and ovarian cancer diagnosed in the same individual
• Breast or ovarian cancer diagnosed in two close relatives, diagnosed at any age
• Ovarian cancer diagnosed in 2 or more close relatives
• Ashkenazi Jewish ancestry and breast cancer diagnosed < age 50
• Ashkenazi Jewish ancestry and breast cancer diagnosed at any age IF family history of breast and/or ovarian cancer is present
• Ashkenazi Jewish ancestry and ovarian cancer diagnosed at any age

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Hereditary NonPolyposis Colon Cancer (HNPCC)

Any family that meets the following criteria should be considered an appropriate referral for diagnostic services and genetic testing:

Amsterdam Criteria (3-2-1 rule)

• 3 relatives with colorectal cancer (One is a first degree relative of the other two) AND
• 2 successive generations affected AND
• 1 colorectal cancer diagnosed < 50

• Families that meet Amsterdam Criteria
• Any colorectal cancer or endometrial cancer diagnosed < age 45
• 2 HNPCC Individuals who have two HNPCC-related cancers (endometrial, ovarian, small bowel, renal pelvis, ureter, gastric, hepatobillary, synchronous/metachronous colorectal cancers); OR
• Individuals with colorectal cancer and a first-degree relative with colorectal cancer and/or HNPCC-related extracolonic cancer and/or a colorectal adenoma. One of the cancers must have been diagnosed at age < 45 years and the adenoma at age < 40 years; OR
• Individuals with colorectal cancer or endometrial cancer diagnosed at age < 45 years; OR
• Individuals with right-sided colon cancer with an undifferentiated pattern (solid/cribiform) diagnosed at < 45 years; OR
• Individuals with signet ring cell type colorectal cancer (> 50% signet ring cells) diagnosed at < 45 years; OR
• Individuals with colorectal adenoma diagnosed at < 40 years

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Familial Adenomatous Polyposis (FAP)

Any person presenting with polyposis and/or early onset colorectal cancer should be referred for genetic cancer risk assessment and possible genetic testing.

Cowden Syndrome

Any personal or family history of:

• Premenopausal breast cancer or
• Follicular/papillary thyroid cancer

• Other breast or thyroid disease (benign or malignant)
• Multiple hamartomatous lesions of skin, mucous membrane
• Cutaneous facial trichilemmomas
• Macrocephaly
• Uterine fibroids/carcinoma

Li-Fraumeni Syndrome

Any personal or family history or early onset breast cancer (diagnosed < age 35) plus:

• Bone or soft tissue sarcoma
• Brain cancer
• Leukemia
• Adrenocortical carcinoma

• Family history of melanoma in two or more close relatives
• Personal history of multiple primary melanomas, with or without family history
• Dysplastic nevi with personal or family history of melanomas

• Pituitary tumors (prolactinoma)
• Pancreatic tumors (gastrinoma, insulinoma)

• Parathyroid hyperplasia
• Pheochromocytoma
• Marfanoid body habitus
• Ganglioneuromatosis
• Mucosal neuroma

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IDENTIFY A HIGH RISK PATIENT

Brief family-history questionnaires are available for your use. Please contact us at 732-235-7110 for more information.

REFER TO CINJ

To refer a patient to The Cancer Institute of New Jersey’s Cancer Risk Assessment and Counseling Program, simply call our intake coordinator at 732-235-7110.

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REFER TO OTHER GENETICS PROGRAMS

Other cancer genetics programs in the New York, New Jersey, and Pennsylvania area include the following:

New York

Albany Medical Center
518-262-5120

Albert Einstein College of Medicine
Cancer Research Center
718-430-3739

Albert Einstein College of Medicine
Montefiore Medical Center
718-405-8150

Beth Israel Medical Center
Division of Medical Genetics
212-420-4179

Ferre Institute, New Hartford
Genetic Counseling Program
607-724-4308

Ferre Institute- Mohawk Valley Genetic Services
888-483-3773

Memorial Sloan Kettering Cancer Center
Clinical Genetics Services
212-434-5132

Mt. Sinai School of Medicine
Ruttenberg Cancer Center
212-659-5411

New York Medical Center of Queens
718-670-2110

New York Presbyterian Hospital- Cornell
212-746-0299

North Country Genetics Service
315-265-2652

North Shore Long Island Jewish Health System
718-470-3010

North Shore University Hospital
516-365-3996

St. Lukes- Roosevelt Hospital
212-523-7092

Upstate Medical University
315-464-7610

Weill Medical College
Cornell University
212-746-2208

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New Jersey

The University of Medicine and Dentistry of New Jersey-The New Jersey Medical School, Newark
The Center for Human and Molecular Genetics
973.972.3300
Genetic Counselor: Jill Baran, MS, CGC
Geneticist: Beth A. Pletcher, MD

The Atlantic Health System (Morristown Memorial Hospital,
Mountainside Hospital, Overlook Hospital)
888.685.6694
Clinic Coordinator: MaryEllen Van de Moere
Genetic Counselor: Janice Berliner, MS, CGC

The Cooper Health System, Camden
Cancer Risk Evaluation Center
865.325.6764
Genetic Counselor: Faye Shapiro, MS
Medical Oncologist: Generosa Grana, MD

Englewood- Mt. Sinai, Englewood
Cancer Risk Assessment and Counseling Program
201.894.3313
Genetic Counselor: Sherry Campbell Grumet, MA, MS, CGC

Hackensack Medical Center, Hackensack
201.996.5264
Genetic Counselors: Sivya Twersky, MS, CGC;
Adi Bar-Lev, MS; Julie McCarrier, MS

Monmouth Medical Center
888.622.7475
Clinic Coordinator: MaryEllen Van de Moere
Genetic Counselor: Jill Baran, MS, CGC

The St. Barnabus Health Care System (Livingston, NJ)
The Breast Center
973.322.7745
Genetic Counselor: Niecee Singer, MS, CGC

St. Peter's University Hospital
Division of Genetics
732.745.6659
Genetic Counselor: Michelle Horner, MS, CGC

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Pennsylvania

Albert Einstein Medical Center
215-456-8722

Allegheny General Hospital
421-359-8064

Crozer Chester Medical Center
610-447-2678

Fox Chase Cancer Center
Family Risk Assessment Program
215-728-2727

Magee- Womens Hospital
412-641-6188

Northeast Regional Cancer Institute
570-941-7984

Penn State Cancer Institute
717-531-1631

Thomas Jefferson University Hospital
215-955-1011

University of Pennsylvania
Cancer Center
215-349-8143

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ADDITIONAL RESOURCES

To locate cancer genetic services in other areas of the country (or internationally), we recommend the following resources:

The National Society of Genetic Counselors can help you locate a genetic counselor in your area. Their Web site is http://www.nsgc.org.
You may contact them via e-mail at FYI(at)nsgc.org.
Their mailing address is:
National Society of Genetic Counselors
233 Canterbury Drive
Wallingford, PA 19086-6617

The National Cancer Institute also has a directory of cancer genetics professionals at http://www.cancer.gov/search/geneticsservices.

ORDERING BROCHURES

To order brochures for your patients about the Cancer Risk Assessment and Counseling Program at The Cancer Institute of New Jersey, please contact us at 732-235-9374.

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